Bacillus Calmette-Guérin (BCG) complications associated with primary immunodeficiency diseases

Variability of Bcg Strains (bacillus Calmette-guérin)

Three different cultures of BCG propagated for over 2 years in a liquid medium containing Tween 80 and albumin were found to differ in several of their intrinsic properties. Cultures of the three strains were found to consist of morphologically heterogeneous populations-each culture being made up of three main colonial types-spreading, intermediate, and non-spreading. The percentage distributio...

Disseminated Bacillus Calmette-Guérin Infection and Immunodeficiency

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 13, No. 5, May 2007 799 Jennifer Cuellar-Rodríguez,* Arturo Galindo-Fraga,* Víctor Guevara,* Carolina Pérez-Jiménez,* Luis Espinosa-Aguilar,* Ana Lilia Rolón,* Araceli Hernández-Cruz, * Esaú López-Jácome,* Miriam Bobadilla-del-Valle,* Areli Martínez-Gamboa,* Alfredo Ponce-de-León,* and José Sifuentes-Osornio* *Instituto Nacional de Ciencias ...

Systemic bacillus Calmette-Guérin (BCG) activates natural suppressor cells.

Addition of normal C57BL/6 mouse bone marrow cells to an in vitro culture of normal C57BL/6 spleen cells and allogeneic P815-Y tumor cells inhibited the development of cell-mediated immunity. Bacillus Calmette-Guérin (BCG) enhanced the suppressive activity of these bone marrow cells as early as 2 days after its intravenous administration to donor mice and elicited similar activity in the spleen...

Disseminated Bacillus Calmette-Guérin Disease after BCG Vaccination: A Case Report from China

Background: Bacillus Calmette-Guérin (BCG) vaccination is recommended for newborn infants worldwide to prevent tuberculosis. However, complications do occur inevitably in a very low rate, among which the most serious is disseminated disease. The disseminated bacillus Calmette–Guérin disease is a rare disease with high fatality, and can be seen among persons with an underlying immunodeficiency. ...

BCG: who were Calmette and Guérin?